Formulation and Evaluation of Pulsatile Drug Delivery System of Atenolol
نویسندگان
چکیده
The objective of the present study was formulation and evaluation pulsatile release tablets Atenolol. A tablet system consisting cores which coated with layers swelling rupturable coatings. Cores containing Atenolol as model drug were prepared by direct compression appropriate ratios lactose microcrystalline cellulose then sequentially different an inner layer HPMC outer Ethyl Cellulose. effect level coating investigated. press using weight Hydroxy Propyl Methyl Cellulose (HPMC) / (EC) both EC. optimum result achieved in HPMC: EC ratios. F3 batch a highest burst after lag time is applicable delivery
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ژورنال
عنوان ژورنال: Journal of basic and applied research
سال: 2022
ISSN: ['2413-7014']
DOI: https://doi.org/10.51152/jbarbiomed.v6i1.8